US EPA publishes final report on leukaemia-inducing chemicals

The United States Environmental Protection Agency (EPA) has published its final report on the causes of lymphohematopoietic cancers, including industrial chemicals. The report notes that around a quarter of the 100 carcinogenic agents identified to date by the International Agency for Research on Cancer have been shown to induce either leukaemia’s or lymphomas in humans. Many are antineoplastic drugs, but a variety of other agents including industrial chemicals, various forms of radiation, immunosuppressive drugs, and infectious agents have also been shown to induce lymphohematopoietic cancers in humans. The document provides an overview of the types of mechanisms underlying the link between chemicals and these conditions, with particular focus on leukaemia, to examine how mechanistic information can inform risk assessment. A copy of the final report is available at: Final Report

Chemical Watch, 13 July 2012 ; ;