28 REACH Testing proposal consultations launched

On 26 March 2018, the European Chemicals Agency (ECHA) started a 45 day public commenting period on 28 testing proposals for the following substances:

  • 3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione [EC# 401-540-3]
  • 2,4,4-trimethylpentene [CAS# 25167-70-8]
  • 2-methylpentane-2,4-diol [CAS# 107-41-5]
  • 4,4’-methylenebis[2,6-diethylaniline] [CAS# 13680-35-8]
  • Alkyl amine and alkylbenzenesulphonate Tris(2-butoxyethyl) phosphate [CAS# 78-51-3]
  • 1,1’-isopropylidenebis(p-phenyleneoxy) dipropan-2-ol [CAS# 116-37-0]
  • 1,2,3,4-tetrahydronaphthalene [CAS# 119-64-2]
  • 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues [CAS# 68609-68-7]
  • 2,2’-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] [CAS# 23235-61-2]
  • 2-chloropropane [CAS# 75-29-6]
  • 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide [EC# 939-581-9]
  • 6’-(dibutylamino)-3’-methyl-2’-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one [CAS# 89331-94-2]
  • Barium chloride [CAS# 10361-37-2]
  • Bis(2-(2-butoxyethoxy)ethoxy)methane [CAS# 143-29-3]
  • Dimethoxymethane [CAS# 109-87-5]
  • Dipotassium hexachloroplatinate [CAS# 16921-30-5]
  • Hexachloroplatinic acid [CAS# 16941-12-1]
  • Inorganic phosphorus salt [EC# 428-310-5]
  • Phenol, isopropylated, phosphate (3:1) [CAS# 68937-41-7]
  • Slags, ferromanganese-manufg. [CAS# 69012-28-8]

REACH requires that information on toxic effects of substances is obtained by manufacturers and importers of substances, however REACH also requires that new testing of a substance involving vertebrate animals is only carried out as a last resort. To ensure that the best use has been made of existing information, ECHA publishes all test proposals involving vertebrate animals before the testing is carried out. After a testing proposal has been published, third parties have 45 days to submit “scientifically valid information and studies that address the relevant substance and hazard endpoint, relating to the testing proposal” (REACH, Article 40 (2)). The deadline for submitting comments is 11 May 2018.

Chemtrac, 27 March 2018 ; https://www.chemtracglobal.com/news