A case study on co-exposure to a mixture of organic solvents in a Tunisian adhesive-producing company

This study assessed environmental and biological monitoring of exposure to organic solvents in a glue-manufacturing company in Sfax, Tunisia. Exposure of volunteer workers, in the solvented glue-workstations, in the control laboratory and in the storage rooms of the finished products, was assessed through indoor-air and urine measurements. Informed consent of the workers was obtained. The exposure indexes were found with high values in the solvented workshop as well as in the control laboratory and were respectively, 8.40 and 3.12. in addition. these indexes were correlated with hexane and toluene indoor air concentrations. As to urine, the obtained results for the 2,5-hexanedione and hippuric acid, metabolites of hexane and toluene, respectively, were in accord with the indoor-air measurements, with an average of 0.46 mg/l and 1240 mg/g of creatinine. This study assessed for the first time biological exposure to organic solvents used in Tunisian adhesive industries. The authors concluded that although values are likely to underestimate true exposure levels, some figures exceed European and American occupational exposure guidelines.

Authors: Gargouri, Imed; Khadhraoui, Moncef; Nisse, Catherine; Leroyer, Ariane; Masmoudi, Mohamed L.; Frimat, Paul; Marzin, Daniel; Elleuch, Boubaker; Zmirou-Navier, Denis ;Full Source: Journal of Occupational Medicine and Toxicology (London, United Kingdom) [fusion_builder_container hundred_percent=”yes” overflow=”visible”][fusion_builder_row][fusion_builder_column type=”1_1″ background_position=”left top” background_color=”” border_size=”” border_color=”” border_style=”solid” spacing=”yes” background_image=”” background_repeat=”no-repeat” padding=”” margin_top=”0px” margin_bottom=”0px” class=”” id=”” animation_type=”” animation_speed=”0.3″ animation_direction=”left” hide_on_mobile=”no” center_content=”no” min_height=”none”][online computer file] 2011, 6, 28 (Eng) ;