Acute effect of air pollutants (carbon monoxide and ozone) on myocardial infarction mortality in Ningbo

In this study, the authors explored the effect of carbon monoxide (CO) and ozone (O(3)) in the air on the myocardial infarction mortality in Ningbo, Zhejiang province, China, from 2011 to 2015. The data of daily air quality surveillance and the causes of deaths in Ningbo from 1 January 2011 to 31 December 2015 were collected and the time series study using a generalised additive model was conducted to evaluate the relationship between the mortality of myocardial infarction and the air pollutants after adjustment for the long-term trend of death, weather conditions,” days of the week” and other confounding factors. The daily average concentrations of CO and O(3) in Ningbo during 2011-2015 were 0.90 (0.02-3.31) mg/m(3) and 82.78 (4-236) ?g/m(3), respectively. A total of 5 388 myocardial infarction deaths occurred, with a daily average of 3 deaths. In single-pollutant model, an increase of 0.1 mg/m(3) in average concentration of CO could increase the risk of myocardial infarction mortality by 1.06% (95% CI: 0.29%-1.93%) in general population, and by 1.26% (95% CI:0.28%-2.24%) in aged people aged ?65 years in lagged 6 days, but the influence was not significant in people aged <65 years. The influence had no significant difference in males, but it increased the risk of myocardial infarction mortality by 1.77% in females (95% CI: 0.44%-3.13%). In multi-pollutant model, CO did remain robust after adjusting for other co-pollutants. Whereas the effect of O(3) had no significant influence. The authors concluded that these findings suggest that the increased risk of daily myocardial infarction mortality was associated with the increase of CO concentration, but no such association was found for O(3) in Ningbo. Authors: Qian XJ, Li GX, He TF, Li H, Huang J, Xu GZ, Guo XB, Li L. ;Full Source: Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Mar 10;38(3):297-302. doi: 10.3760/cma.j.issn.0254-6450.2017.03.005. ;