Evaluation of Association between Biomarkers of Lead Exposure in Sardinian Children (Italy)

In this study, the authors verified whether there are statistically significant correlations between the concentrations of Pb in blood, urine, and hair in children. The sample collected in 2007 consists of 163 children of both sexes from 11-14-yr-olds, living in 3 municipalities of Sardinia (Italy). Inductively coupled plasma atomic mass spectrometry was used in the detection of Pb concentration in biological material. The results showed that for the overall sample, there is a non-significant partial correlation among the 3 matrixes. However, for subjects with blood Pb levels g5 íg/dL, there is a significant positive partial correlation between the Pb levels in blood and hair, but not between blood and urine or between urine and hair. The authors concluded that the results suggest that blood is the preferred biomarker to ascertain Pb exposure in human populations, whereas hair can be used as a tool screening when an area is exposed to medium or high lead pollution.

Authors: Sanna, Emanuele; Micco, Alessandro; Vallascas, Elisabetta ;Full Source: Biological Trace Element Research [online computer file] 2011, 143(3), 1383-1392 (Eng) ;