Health ranking of ingested semi-volatile organic compounds in house dust: an application to France

People spend most of their time indoors. Dust settled in the home may be contaminated by semi-volatile organic compounds (SVOCs). Exposure to these compounds is of great concern, in particular for infants. Their number is large so arose the question of which ones should be selected for dust ingestion exposure assessment. In this study, the authors propose a health ranking of SVOCs ingested through settled dust. This ranking is based on the toxicity and contamination of SVOCs in dust. Data on compounds and contamination was retrieved from a bibliography review. Where possible, toxicity data was retrieved from databases, otherwise it was calculated from raw data. One hundred and fifty-six SVOCs were selected, 66 of which were prioritised. Forty-two could not be prioritised because contamination data was below the limit of detection, and 48 could not be prioritised because there was no contamination or toxicity data. The top-ranked compounds were phthalates, pesticides, short-chain chlorinated paraffins, PBDEs, PFCs, organotins, PCBs, and PAHs. The authors concluded that as most of these have reprotoxic and neurotoxic properties, an integrated multi-pollutants approach to exposure is required and simultaneous measurement methods should be developed.

Authors: Bonvallot, N.; Mandin, C.; Mercier, F.; Le Bot, B.; Glorennec, P. ;Full Source: Indoor Air 2010, 20(6), 458-472 (Eng) ;