Insight into the behaviour of engineered aerosolised nanoparticles a method for understanding their fate from an aerosol release in the workplace environment

In this study, the authors assessed the behaviour of aerosol nanoparticles as a function of time and of selected aerosol chamber and environmental conditions upon exposure to polydisperse silicon dioxide (SiO2) aerosol nanoparticles (NPs). Through synthesis of SiO2 aerosol NPs, a well-controlled, stable source of aerosol NPs was used to probe aerosol behaviour in an enclosed aerosol chamber. This study described a procedure to interface an aerosol chamber downstream of a SiO2 aerosol NP reactor that is capable of synthesising SiO2 NPs with particle diameters from 10 to 100 nm at particle concentrations of approximately 104 to 107 particles/cm3. In addition, the authors describe the relative impact on aerosol and aerosol chamber variables, such as chamber volume, the entering aerosol NP size distribution, and environmental parameters, such as relative humidity and ambient particle concentrations, on the observed changes in aerosol NPs over time under unmixed conditions. The authors concluded that these findings provide insights into aerosol NP behaviour under ideal, well-controlled conditions which can be further refined to include more occupationally relevant conditions that would be important for establishing guidance on suitable workplace containment and controls.

Authors: Ostraat, Michele L.; Swain, Keith A.; Small, Robert J. ;Full Source: International Journal of Occupational and Environmental Health 2010, 16(4), 458-466 (Eng) ;