Respirable organic chemicals were originally thought to cause allergic respiratory diseases, such as bronchial asthma and hypersensitivity pneumonitis, and believed not to cause lung disorders derived from inflammatory or fibrotic processes such as pulmonary fibrosis and interstitial pneumonitis. It has recently been reported, however, that exposure to organic chemicals can cause interstitial lung diseases. In this review, we discuss the clinical features of occupational asthma and hypersensitivity pneumonitis, as well as other lung disorders, including interstitial pneumonitis, caused by humidifier disinfectants in Korea and by a cross-linked acrylic acid-based polymer (CL-PAA) in Japan.
Authors: Yasuo Morimoto, Chinatsu Nishida, Taisuke Tomonaga, Hiroto Izumi, Kazuhiro Yatera, Kazuo Sakurai, Yangho Kim
; Full Source: Journal of occupational health 2021 Jan;63(1):e12240. doi: 10.1002/1348-9585.12240.