Multifocal osteonecrosis secondary to occupational exposure to aluminium

Multifocal osteonecrosis is a rare disease; chronic use of corticosteroids is considered the main risk factor. Patients with chronic renal failure can develop aluminium toxicity, which can lead to osteomalacia and encephalopathy. An association between osteonecrosis and aluminium toxicity has been reported among patients with dialytic renal insufficiency. Occupational exposure to aluminium rarely causes lung disease and no cases of bone lesions resulting from exposure to this metal have been reported. In this study, the authors describe a novel case of a patient with multifocal osteonecrosis associated with chronic occupational exposure to aluminium. Level of Evidence IV, Case Report.

Authors: Assunção JH, Malavolta EA, Gracitelli MEC, Filippi RZ, Ferreira AA Neto. ;Full Source: Acta Ortopédica Brasileira. 2017 May-Jun;25(3):103-106. doi: 10.1590/1413-785220172503170760. ;