In this study, concentrations and profiles of 16 polybrominated di-Ph ether (PBDE) congeners, 3 hexabromocyclododecane (HBCD) isomers, and 6 alternative brominated flame retardants (BFR) in dust collected from 25 Czech households and 27 car interiors were assessed. The ª16 PBDE content varied widely with maximum concentrations up to 5896 and 33728 íg/kg in house and car dust, respectively. Highest PBDE concentrations were observed for PBDE 209, which occurred in nearly all samples and which exceeded concentrations of other PBDE, even by 1 order of magnitude. Concentrations and profiles of penta-, octa-, and decaBDE were comparable to those in other studies worldwide and confirmed lower dust contamination in Europe versus North America. From alternative BFR, suitable for common applications as alternatives to banned PBDE, decabromodiphenyl ethane and HBCD were mainly detected at concentrations of <20-3567 and <0.3-950 íg/kg, respectively; ç-HBCD was dominant, comprising up to 70% of ªHBCD. Using measured concentrations and dust ingestion rate estimates, it was estimated that toddlers had a higher exposure than adults for all studied compounds.