Perception of risk of exposure in the management of hazardous drugs in home hospitalization and hospital units


Objective: To assess the perception of risk of exposure in the management of hazardous drugs (HDs) through home hospitalization and hospital units.

Material and methods: A questionnaire was released, at the national level, to health professionals with HD management expertise. Questionnaire included 21 questions that were scored using a Likert scale: 0 (null probability) to 4 (very high probability). The internal consistency and reliability of the questionnaire were calculated using Cronbach’s alpha and the intraclass correlation coefficient, respectively. Results: 144 questionnaires (response rate 70.2%) were obtained: 65 (45.1%) were nurses, 42 (28.9%) occupational physicians, and 37 (26.1%) were pharmacists. Cronbach’s alpha was 0.93, and intraclass correlation coefficient was 0.94 (95% CI 0.91-0.97; p-value < 0.001). The mean probability was 1.95 ± 1.02 (median 1.9; minimum: 0.05; 1st quartile 1.1; 3rd quartile 2.6; and maximum 4). Differences were observed in scoring among professional groups (occupational physicians versus nurses (1.6/2.1, p = 0.044); pharmacists versus nurses (1.7/2.1, p = 0.05); and occupational physicians versus pharmacists (1.6/1.7, p = 0.785), due mainly to the administration stage (p = 0.015).

Conclusions: The perception of risk of exposure was moderate, being higher for nurses. It would be advisable to integrate HDs into a standardized management system (risk management model applicable to any healthcare center) to improve the safety of health professionals.

Authors: Mari Ángeles Bernabeu-Martínez, Julia Sánchez-Tormo, Pedro García-Salom, Javier Sanz-Valero, Carmina Wanden-Berghe
; Full Source: PloS one 2021 Jul 1;16(7):e0253909. doi: 10.1371/journal.pone.0253909.