Primary survey on oxidative stress reaction in workers exposed to low level of phosgene

During this study, the authors recruited a total of 179 workers exposed to low level of phosgene, and another 153 healthy workers exposed to no occupational health hazard as controls. The serum content of malondialdehyde (MDA) and the serum activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) were detected. The results showed that the content of MDA and the activity of SOD in serum of workers exposed to low level of phosgene were higher than those of controls (P < 0.01). The serum activity of GSH-Px was lower in serum of workers exposed to low level of phosgene than in serum of controls, but there was statistical difference in workers younger than 30 years (P < 0.05).

Authors: Liu, Jing; Shou, Yongming; Zhang, Ye; Zhang, Jin; Bao, Xiaolu; Jin, Fusheng ;Full Source: Zhongguo Gongye Yixue Zazhi 2011, 24(5), 386-387 (Chinese) ;