This is a review. Tibolone was a selective tissue oestrogen activity regulator (STEAR), and was mainly used for releasing vasomotion during perimenopause, improving urogenital tract atrophy, preventing osteoporosis, etc. The paper reviewed the clinical application, the probable clinical application, the safety (bad effects on mammary gland neoplasm cardiovascular and cerebrovascular systems, no bad effect on endometrium), and the drug resistance of tibolone.
Authors: Xiong, Min; Huang, Wei. ;Full Source: Shiyong Fuchanke Zazhi 2011, 27(8), 580-583 (Ch) ;