Serum LN, C-IV and HA levels and pathological observation in cement induced lung fibrosis patients and lung fibrosis model rats

The serum levels of laminin (LN), collagen IV (C-IV) and hyaluronidase (HA) in patients with lung fibrosis induced by cement dust and model rats of lung fibrosis were detected and compared with controls. The results showed that the serum levels of LN, C-IV and HA were significantly higher in patients and rats with lung fibrosis than in controls. The detection of the serum levels of LN, C-IV and HA was helpful for the diagnosis of lung fibrosis induced by cement dust.

Authors: Lin, Kaiyan; Gu, Minghong; Cen, Rongguang; Liu, Yunlin; Yang, Xiuyi; Jiang, Qiang ;Full Source: Zhongguo Gongye Yixue Zazhi 2011, 24(5), 362-363 (Chinese) ;