Serum perfluoroalkyl acids (PFAAs) and associations with behavioural attributes

The ubiquitous use of poly- and perfluoroalkyl substances (PFASs) in a variety of industrial and consumer products has resulted in chronic exposure in most industrialised nations, and led to measurable concentrations in blood and other tissues in humans across all life stages; however, behavioural attributes that relate to exposure are not well studied. To further investigate how behaviour may relate to PFAS exposure, 37 adults were recruited from central North Carolina. Participants provided blood samples and behavioural questionnaires were administered, asking questions about a variety of household, dietary, and behavioural outcomes. Six PFAAs, including PFHxA (geometric mean: 0.14 ng/mL), PFOA (1.57 ng/mL), PFNA (0.67 ng/mL), PFDA (0.28 ng/mL), PFHxS (3.17 ng/mL) and PFOS (4.96 ng/mL) were detected in >50% of the samples. Generally, males had higher serum levels than females across all chemicals, and levels were very similar to NHANES levels; however, PFHxS and PFDA levels were higher in our study population. Several personal characteristics and behaviours were associated with serum PFAS levels. Reported use of filtration devices was associated with lower levels of PFOA (28% lower, p = 0.03), but higher levels of PFHxA (122% higher, p = 0.04). Serum PFHxS levels were also elevated in individuals that vacuumed less often, and in individuals that reported consuming more microwavable foods. The authors concluded that these results suggest that personal behaviours may be important determinants of PFAS exposures.

Authors: Siebenaler R, Cameron R, Butt CM, Hoffman K, Higgins CP, Stapleton HM. ;Full Source: Chemosphere. 2017 Jun 9; 184:687-693. doi: 10.1016/j.chemosphere.2017.06.023. [fusion_builder_container hundred_percent=”yes” overflow=”visible”][fusion_builder_row][fusion_builder_column type=”1_1″ background_position=”left top” background_color=”” border_size=”” border_color=”” border_style=”solid” spacing=”yes” background_image=”” background_repeat=”no-repeat” padding=”” margin_top=”0px” margin_bottom=”0px” class=”” id=”” animation_type=”” animation_speed=”0.3″ animation_direction=”left” hide_on_mobile=”no” center_content=”no” min_height=”none”][Epub ahead of print] ;[/fusion_builder_column][/fusion_builder_row][/fusion_builder_container]