The effect of cadmium exposure on diversity of intestinal microbial community of Rana chensinensis tadpoles

Cadmium is a natural and widely distributed toxicant and can be commonly found in environment. Intestinal microbiota plays a very important role in maintaining its host’s health. The effects of cadmium on the intestinal microbiota composition and stability of amphibians are little known. In this study, the authors exposed Rana chensinensis (R. chensinensis) embryos to different concentrations of cadmium (0, 112 and 448??g?Cd?L-1) until they reached Gosner stage 38, and analysed their microbial communities using 16S rRNA amplicon sequencing. By measures of both alpha and beta diversity, intestinal microbial communities were significantly differentiated in 448??g?Cd?L-1 exposure groups. Cadmium exposure significantly altered the intestinal microflora diversity and composition of R. chensinensis. At the phylum level, it is worth noting that Fusobacteria and Spirochaetae were not detected in 448??g?Cd?L-1 exposure groups. Firmicutes rapidly decreased in 448??g?Cd?L-1 exposure group. At the genus level, Succinispira (Firmicutes), Desulfovibrio (Proteobacteria) and Fusobacterium (Fusobacteria) vanished in 448??g?Cd?L-1 exposure groups. The results demonstrate that cadmium exposure changed the composition and decreased the community diversity of intestinal microbiota of R. chensinensis tadpoles. The authors concluded that this study may provide a new framework based on intestinal microbiota to evaluate the response of amphibians to environmental chemicals pollution.

Authors: Mu D, Meng J, Bo X, Wu M, Xiao H, Wang H. ; Full Source: Ecotoxicology & Environmental Safety. 2018 Feb 13; 154:6-12. doi: 10.1016/j.ecoenv.2018.02.022. [fusion_builder_container hundred_percent=”yes” overflow=”visible”][fusion_builder_row][fusion_builder_column type=”1_1″ background_position=”left top” background_color=”” border_size=”” border_color=”” border_style=”solid” spacing=”yes” background_image=”” background_repeat=”no-repeat” padding=”” margin_top=”0px” margin_bottom=”0px” class=”” id=”” animation_type=”” animation_speed=”0.3″ animation_direction=”left” hide_on_mobile=”no” center_content=”no” min_height=”none”][Epub ahead of print][/fusion_builder_column][/fusion_builder_row][/fusion_builder_container]