Thyroid function and its relationship with pulmonary ventilation function in patients of coal workers’ pneumoconiosis

This study discussed the correlation of thyroid function with pulmonary ventilation function in patients of coal workers’ pneumoconiosis. Sixty-eight patients of coal workers’ pneumoconiosis and 38 normal cases were chosen. Serum TT3, TT4, FT3 and TSH were detected by RIA; pulmonary ventilation function indexes: VC, FVC, FEV1%, V25, V50, MVV were also detected. TT3 and TT4 in stage II+III group were decreased, TSH was increased, and there was statistical significance compared with control group and stage I group (P<0.05). Pulmonary ventilation function indexes in patients of coal workers' pneumoconiosis were lower than those in control group (P<0.05). Pulmonary ventilation function indexes in stage II+III group were lower than that in stage I group (P<0.05), and there was statistical significance. Abnormal rate of pulmonary ventilation function indexes in patients of coal workers' pneumoconiosis was higher than that in control group (P<0.05), and there was statistical significance. With increase of stage and lung injury in patients of coal workers' pneumoconiosis, thyroid function was changed.

Authors: Sun, Kuo; Sun, Yan; Bao, Chundan; Wang, Liping; Liu, Xinyan; Liu, Ying; Dong, Shuying ;Full Source: Zhongguo Gongye Yixue Zazhi 2012, 25(2), 107-108 (Chinese) ;