Toxidromes aid emergency care providers in the context of the patient presenting with suspected poisoning, unexplained altered mental status, unknown hazardous materials or chemical weapons exposure, or the unknown overdose. The ability to capture an adequate chemical exposure history and to recognise toxidromes may reduce dependence on laboratory tests, speed time to delivery of specific antidote therapy, and improve selection of supportive care practices tailored to the etiologic agent. This article highlights elements of the exposure history and presents selected toxidromes that may be caused by toxic industrial chemicals and chemical weapons. Specific antidotes for toxidromes and points regarding their use, and special supportive measures, are presented.
Authors: Tomassoni AJ, French RN, Walter FG. ;Full Source: Emergency Medicine Clinics of North America. 2015 Feb;33(1):13-36. doi: 10.1016/j.emc.2014.09.004. Epub 2014 Nov 15. ;