Erasmus Syndrome: Silicosis and Systemic Sclerosis

Several occupational hazards, especially exposure to silica, have been implicated as causal factors for the development of scleroderma-like disorders. Compared to other connective tissue disorders, silica-associated systemic sclerosis (SA-SS) is relatively rare. Silica-induced scleroderma is indistinguishable from idiopathic systemic sclerosis. However, the former expresses a high predisposition of pulmonary involvement and anti-Scl-70 antibody. In this study, the authors report the case of a 42-year-old male, stone cutter by occupation, who was diagnosed as simple chronic silicosis and developed systemic sclerosis.

Authors: Jain S, Joshi V, Rathore YS, Khippal N. ; Full Source: Indian Journal of Occupational & Environmental Medicine. 2017 May-Aug;21(2):94-96. doi:10.4103/ijoem.IJOEM_120_17.

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